I-64 traffic backup near the 105 mile marker Tuesday afternoon. Screen image courtesy of Trafficland.com 
NCL has confirmed that a major accident involving two 18 wheelers is being worked on I-64 between the 104 and 105 MM westbound. That is roughly 4-5 miles east of the Afton Mountain exit, but not quite to the Crozet exit, 107. The right lane of traffic is totally blocked, but vehicles are getting through, slowly in the left lane westbound.
One of the vehicles is leaking diesel fuel, no word on injuries. you can see in the image above that traffic is slowing down as it travels.
More as we have it.